Patau Syndrome: A Rare Autosomal Trisomy

Shahnaz Akter, Assistant Registrar, Department of Pediatrics, Institute of Child & Mother Health, Dhaka, Bangladesh

Wahida Khanam, Assistant Professor, Department of Pediatrics, Institute of Child & Mother Health, Dhaka, Bangladesh

Ahsanul Haque, Registrar, Department of Pediatrics, Institute of Child & Mother Health, Dhaka, Bangladesh

Rahmat Ali, Assistant Registrar, Department of Pediatrics, Institute of Child & Mother Health, Dhaka, Bangladesh

Md Abdul Halim, Professor, Department of Pediatrics, Institute of Child & Mother Health, Dhaka, Bangladesh

Introduction:
Patau syndrome, also known as trisomy 13 or trisomy D, is the least common and most severe
of the viable autosomal trisomies. Incidence of Patau syndrome is approximately 1 case per 10,000 live births1. The syndrome results from an extra copy of chromosome 13, due to meiotic nondisjunction or sometimes by Robertsonian translocations. Karyotypes of Patau syndrome may be one among: Trisomy 13 type: 47,XX,+13, Translocation type: 46,XX(14;21)(q10;q10)+13, Mosaic type: 46,XX/47,XX+13. Although specific etiologic factors......

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