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Original Article
Vitamin-D Level in Children with Bronchiolitis Attending a Selected Tertiary Hospital
Md. Delwar Hossain, Tania Islam, S M Zahid Hassan Arefin, Mohammad Abdur Razzaque, Mahbub Ahmed, A.K. Naseruzzaman, Asma Mahmud, Md. Shahnoor Karim, Anup Kumar Saha, Ifthakhar Ahmed, Bidhan Chandra Podder
Keywords:
Vitamin D, Bronchiolitis, Sun Light Exposure.
Abstract
Background: Vitamin D can augment the innate and adaptive immune systems of the human body.
Thus vitamin-D (25-hydroxy vitamin D) levels are inversely associated with respiratory infections
like bronchiolitis.
Objective: To determine the status of Vitamin D-25(OH) D level in children with bronchiolitis.
Methods: A case-control study was conducted in ICMH from January to June 2019. Thirty-one
children 1 month to < 24 months of age with bronchiolitis as defined by working definition and
attending to the inpatient and outpatient departments were enrolled as a case group. Thirty-two
children of the same age and sex-matched group without any respiratory illness attending the
outpatient and EPI center were taken as a control group. Parents’ informed consent was taken
before enrolling either the cases or the control group in the study. Data were collected in a
pretested structured questionnaire. Venous blood samples were collected from both groups in
aseptic conditions and sent to the immunology department to measure their vitamin D level (Vit-D).
Results: A total of 63 children were studied; 31cases and 32controls. The mean age of cases was
6.72±4.29 and controls were 8.53±4.99. Vit-D levels were found deficient more in the control group
than in the case group, 18(56.2%) vs 14(45.2%) respectively. But the insufficient level was found
more in cases than in the control, 11(35.5%) vs 8(25.0%). Only about one-fifth of the study
participants had sufficient Vit-D levels, 6(19.3%) and 6(18.7%) in the case and control groups
respectively. These differences were not significant statistically. Also, vitamin D levels showed no
significant difference in relation to sun exposure in any studied populations.
Conclusion: This study showed that there was no significant difference in Vit-D levels between the
children with acute bronchiolitis and normal children. Also, the vitamin D level showed no
significant difference in any studied populations who were sun-exposed either adequately or
inadequately.
Published: January 2020
Issue
ICMH Journal 2020; 11(1): 1–2
Section
Original Article
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